Discovery of mcr-3.1 gene carried by a prophage located in a conjugative IncA/C2 plasmid from a Salmonella Choleraesuis clinical isolate

The emergence of mcr-gene posts a serious threat to the use of colistin which is one of the last-resort treatments against human infections caused by MDR Gram-negative bacteria. In this Journal, the discovery of plasmid-mediated colistin resistance gene mcr-3 in poultry fecal samples from China live poultry markets (LPMs) has been recently reported (1, 2). Here, to the best of our knowledge, we report the first case of plasmid-borne mcr-3.1 present in an MDR Salmonella enterica serovar Choleraesuis isolate from human.

Source: Journal of Infection - September 28, 2020 Category: Infectious Diseases Authors: Yuanlong Pan, Yuan Fang, Yuqing Feng, Na Lyu, Luping Chen, Jing Li, Xuebin Xu, Baoli Zhu, Yongfei Hu Tags: Letter to the Editor Source Type: research