Characterization of exhaled breath condensate (EBC) non-exchangeable hydrogen functional types and lung function of wildland firefighters

The objective of
this study was to identify changes in metabolic profile of exhaled breath condensate (EBC) and lung
function of firefighters exposed to wildfires smoke. A total of 29 subjects were studied over 16
events; 14 of these subjects provided cross-shift EBC samples. The predominant types of
non-exchangeable hydrogen in EBC were saturated oxygenated hydrogen, aliphatic alkyl and allylic.
Non-exchangeable allylic and oxygenated hydrogen concentrations decreased in post-exposure EBC
samples. Longer exposures were correlated with increased abundance of oxidized carbon in ketones,
acids and esters. Post-exposure lung function declines (forced expiratory volume in 1 s (FEV 1 ):
0.08 l, fo...

Source: Journal of Breath Research - September 22, 2020 Category: Respiratory Medicine Authors: Jordan Nelson, Marie-Cecile G Chalbot, Zoran Pavicevic and Ilias G Kavouras Source Type: research