Viruses, Vol. 12, Pages 1066: Comment: Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb

Viruses, Vol. 12, Pages 1066: Comment: Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb Viruses doi: 10.3390/v12101066 Authors: Caroline Charre Frédéric le Gal Paul Dény Caroline Scholtès Evidence that Hepatitis D virus (HDV) genotype is involved in HDV infection pathogenesis is increasing. Indeed, HDV genotypes have been shown to be linked to different outcomes in terms of liver fibrosis and treatment response. Herein, we show that the promising HDVdb genotyping tool available online can lead to wrong genotyping results. The current HDVdb algorithm should be carefully considered as a “beta-version” and warrants algorithm core corrections, as soon as possible, for an optimal and beneficial use.
Source: Viruses - Category: Virology Authors: Tags: Comment Source Type: research