Effect of oral minoxidil for alopecia: Systematic review

Israel Junior Borges do Nascimento, Matthew Harries, Vanessa Barreto Rocha, Jacqueline Y Thompson, Chun Hoong Wong, Hamed Kord Varkaneh, Nathália Sernizon Guimarães, Alair Junior Rocha Arantes, Milena Soriano MarcolinoInternational Journal of Trichology 2020 12(4):147-155 Patients with major presentations of alopecia experience physically harmful effects and psychological comorbidities, such as depression and anxiety. Oral minoxidil (OM) has been suggested by dermatologists as a potential remedy; however, its effectiveness remains unclear. This systematic review aims to collate published studies and to analyze the effect of OM among patients diagnosed with any type of alopecia. For this systematic review, Medline/PubMed, Cochrane Central, EMBASE, Web of Sciences, and Latin American and Caribbean Health Sciences Information System were searched for relevant studies from inception to September 21, 2019. Of 1960 studies retrieved in several electronic databases and three additional records identified though reference list from potentially eligible studies, nine studies (one randomized controlled trial and eight nonrandomized controlled trials) met the requirements and were used in our analysis. Although we found positive effects in favor of OM, this should be interpreted cautiously due to very low quality of the evidence of outcomes in the selected studies. Definitive conclusions are not possible without high-quality trials. This review has highlighted the absence of ...
Source: International Journal of Trichology - Category: Dermatology Authors: Source Type: research

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Conclusions: This systematic review and meta-analysis expects to provide high-quality evidence regarding the synergistic effect of Plum-blossom needle plus Chinese herbal medicine treatment for AA.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
IJERPH, Vol. 17, Pages 7160: Understanding the Public’s Emotions about Cancer: Analysis of Social Media Data International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197160 Authors: Seul Ki Park Hyeoun-Ae Park Jooyun Lee Cancer survivors suffer from emotional distress, which varies depending on several factors. However, existing emotion management programs are insufficient and do not take into consideration all of the factors. Social media provides a platform for understanding the emotions of the public. The aim of this study was to explore the relationship between the public...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
CONCLUSIONS: Our study showed that the frequency and severity of some dermatological complaints increased in HCPs. PMID: 32975297 [PubMed - in process]
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - Category: Dermatology Tags: Acta Dermatovenerol Alp Pannonica Adriat Source Type: research
Authors: Cakirca G, Manav V, Celik H, Saracoglu G, Yetkin EN Abstract Introduction: Increased oxidative stress (OXS) and a high prevalence of psychiatric disorders are seen in alopecia areata (AA). However, OXS and psychiatric disorders have been studied separately in AA patients. Aim: To determine the effects of anxiety and depression symptoms on OXS in AA patients. Material and methods: The anxiety and depression levels of 33 AA patients and 33 normal controls (NC) were determined using the Hospital Anxiety and Depression Scale. The oxidative stress index (OSI) was calculated by measuring serum total anti...
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
ConclusionsLife with hair loss from scalp ringworm irradiation in childhood has a negative impact on women ’s health status and psychosocial state. Health policy-makers must broaden their approach to women who underwent scalp ringworm irradiation by addressing the effects of their hair loss in addition to the effects of the radiation treatment per se. This may be achieved by guiding physicians who prov ide medical services to these women to take into account the psychosocial and health risks related to hair loss in their diagnosis and treatment as well as by creating a cadre of specially trained mental health profess...
Source: Israel Journal of Health Policy Research - Category: International Medicine & Public Health Source Type: research
Caffeine, particularly after ingestion, is well known to exert various pharmacological effects. A growing body of evidence implicates the ingestion of caffeine with beneficial effects on several diseases. The easy penetration of caffeine across the skin barrier and into human skin makes caffeine an ideal compound for topical application. Hair loss is known to negatively affect the quality of life and predispose to depression and anxiety. Androgenetic alopecia (AGA) is the most common type of hair loss in both men and women. To date, only few approved drug-based treatments for AGA exist, and these are inevitably associated ...
Source: Skin Pharmacology and Physiology - Category: Dermatology Source Type: research
Publication date: Available online 26 December 2019Source: Neurobiology of StressAuthor(s): Silvia Diviccaro, Roberto Cosimo Melcangi, Silvia GiattiAbstractThe presence of side effects during pharmacological treatment is unfortunately a quite common problem. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5α-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA).Although these drugs are generally well tolerated, many reports described adverse effects in men during treatment, such as sexual d...
Source: Neurobiology of Stress - Category: Neuroscience Source Type: research
Conclusions: Demographic and social variables, type of TKI-therapy, therapy duration, and depth of response were associated with patient-reported symptoms in persons with chronic phase CML. Certain symptoms have adverse impact on HRQoL.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
AbstractFemale androgenetic alopecia (FAGA) is a common cause of non-scarring alopecia in women. The onset may be at any age following puberty and the frequency increases with age. Clinically, it shows a diffuse hair thinning over the central scalp, while the frontal hairline is usually retained. FAGA can have a significant psychological impact, leading to anxiety and depression. For this reason, early diagnosis is very important to stop the progression of the disease. The sex hormonal milieu is the main pathogenetic mechanism studied in FAGA. The role of androgens is not clearly defined and only one-third of women with FA...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
Background: The psychological effects of alopecia can be massive. Alopecia is associated with a greater risk of anxiety and depression. Patients with alopecia universalis have a
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
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