Comparing predictive values of carbohydrate antigen 19-9, neutrophil gelatinase –associated lipocalin, and kidney injury molecule-1 in 161 patients with ureteropelvic junction obstruction

ConclusionsOur evaluations demonstrate the higher efficacy of CA19-9 to predict the requirement of surgical intervention in comparison with the other biomarkers, as well as a significant correlation between kidney function deterioration and urinary CA19-9 and NGAL. The outcomes of this investigation could pave the way for more extensive clinical application of these urinary biomarkers, besides future research determining the association between markers and kidney fibrosis.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research