Regional variation in patients and outcomes in the GLOBAL LEADERS trial

Despite the overall neutral results of the GLOBAL-LEADERS trial, results from a prespecified subgroup analysis showed that patients from Western Europe had a significantly lower rate of the primary endpoint when treated with ticagrelor monotherapy. Therefore, we aimed to examine the regional disparities in patients' baseline characteristics and their response to ticagrelor monotherapy.

Source: International Journal of Cardiology - September 13, 2020 Category: Cardiology Authors: Chao Gao, Kuniaki Takahashi, Scot Garg, Hironori Hara, Rutao Wang, Hideyuki Kawashima, Masafumi Ono, Gilles Montalescot, Michael Haude, Ton Slagboom, Pascal Vranckx, Marco Valgimigli, Stephan Windecker, Christian Hamm, Philippe Gabriel Steg, Robert Storey Source Type: research