Characterization of a distinct low-grade oncocytic renal tumor (CD117-negative and cytokeratin 7-positive) based on a tertiary oncology center experience: the new evidence from China

We described a group of low-grade oncocytic renal tumors identified retrospectively in a large tertiary cancer center, which was probably the first report originated from China or even Asia in the English literature so far. These tumors demonstra ted eosinophilic cytoplasm and low-grade appearing nuclei with a “CD117 negative/CK7 positive” immunoprofile. The incidence rate was about 3.7% of the oncocytic renal tumors and 0.18% of all the renal tumors that were received in our lab during the four-year period. It is necessary to separate t his group of tumors by its characteristic morphologic and immunophenotypic features.
Source: Virchows Archiv - Category: Pathology Source Type: research