NMDA receptor-mediated CaMKII/ERK activation contributes to renal fibrosis

This study aimed to understand the mechanistic role of N-methyl-D-aspartate receptor (NMDAR) in acute fibrogenesis using models of in vivo ureter obstruction and in vitro TGF- β administration.

Source: BMC Nephrology - September 9, 2020 Category: Urology & Nephrology Authors: Jingyi Zhou, Shuaihui Liu, Luying Guo, Rending Wang, Jianghua Chen and Jia Shen Tags: Research article Source Type: research