Upregulation of microRNA-195 might be a novel therapeutic target in the treatment of aortic valve calcification

I read with great interest the article by Yang et al. [1] revealing that upregulation of miR-195 ameliorated aortic valve calcification by repressing von Willebrand factor (VWF) and p38 mitogen-activated protein kinase (p38-MAPK) signaling pathway. It indicated that miR-195/VWF/p38-MAPK signaling pathway played a critical role in the pathogenesis of calcific aortic valve disease (CAVD) and that may be beneficial in discovering a novel therapy for patients with CAVD.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Letter to the Editor Source Type: research