Manual and semi-automated delineation of locally advanced rectal cancer subvolumes with diffusion-weighted MRI.

CONCLUSION: Contours based on co-registered T2W and DW-MRI could be used for delineation of biologically relevant tumour subvolumes. Semi-automated delineation based on patient-specific intratumoral ADC thresholds may standardise subvolume delineation if registration between acquisitions is sufficiently accurate. ADVANCES IN KNOWLEDGE: This is the first study to evaluate the feasibility of semi-automated diffusion-based subvolume delineation in LARC. This approach could be applied to dose escalation or 'dose painting' protocols to improve delineation reproducibility. PMID: 32877210 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32877210?dopt=Abstract

Source: The British Journal of Radiology - September 1, 2020 Category: Radiology Authors: Hearn N, Bugg W, Chan A, Vignarajah D, Cahill K, Atwell D, Lagopoulos J, Min M Tags: Br J Radiol Source Type: research