Mixing drugs and genetics: a complex hemorrhagic cocktail

A 83-year old Caucasian woman developed a subarachnoid hemorrhage related to multiple drug-drug interactions and polymorphisms of the ABCB1 gene leading to a reduced activity of the P-glycoprotein (P-gp) and high dabigatran plasma levels.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to the editor Source Type: research