Mixing drugs and genetics: a complex hemorrhagic cocktail
A 83-year old Caucasian woman developed a subarachnoid hemorrhage related to multiple drug-drug interactions and polymorphisms of the ABCB1 gene leading to a reduced activity of the P-glycoprotein (P-gp) and high dabigatran plasma levels.
Source: The American Journal of Medicine - Category: General Medicine Authors: Laura Barbolini, Jean Terrier, Christophe Marti, Caroline Samer, Youssef Daali, Pierre Fontana, Jean ‑Luc Reny Tags: Clinical Communication to the editor Source Type: research