Effect of long-term testosterone therapy on molecular regulators of skeletal muscle mass and fibre-type distribution in aging men with subnormal testosterone

Long-term testosterone replacement therapy (TRT) increases muscle mass in elderly men with subnormal testosterone levels. However, the molecular mechanisms underlying this effect of TRT on protein balance in human skeletal muscle in vivo remain to be established.

Source: Metabolism - Clinical and Experimental - August 23, 2020 Category: Biomedical Science Authors: Rikke Kruse, Stine J. Petersson, Louise L. Christensen, Jonas M. Kristensen, Rugivan Sabaratnam, Niels Ørtenblad, Marianne Andersen, Kurt Højlund Source Type: research