TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia.

CONCLUSIONS: TOSO might be involved in the pathogenesis of CLL by interacting with SYK, enhancing the BCR signaling pathway, and inducing apoptosis resistance.
PMID: 32784334 [PubMed - as supplied by publisher]

Source: Chinese Medical Journal - August 9, 2020 Category: General Medicine Authors: Zhang YR, Yu Z, Xiong WJ, Liu XX, Liu HM, Cui R, Wang Q, Chen WM, Qiu LG, Yi SH Tags: Chin Med J (Engl) Source Type: research