Stromal regulation of tufmor-associated lymphatics.

Stromal regulation of tufmor-associated lymphatics.
Adv Drug Deliv Rev. 2020 Aug 09;:
Authors: Munir H, Mazzaglia C, Shields JD
Abstract
Recent advances have identified a growing array of roles played by lymphatics in the tumor microenvironment, from providing a route of metastasis to immune modulation. The tumor microenvironment represents an exceptionally complex, dynamic niche comprised of a diverse mixture of cancer cells and normal host cells termed the stroma. This review discusses our current understanding of stromal elements and how they regulate lymphatic growth and functional properties in the tumor context.
PMID: 32783989 [PubMed - as supplied by publisher]

Source: Advanced Drug Delivery Reviews - August 8, 2020 Category: Drugs & Pharmacology Authors: Munir H, Mazzaglia C, Shields JD Tags: Adv Drug Deliv Rev Source Type: research