Skin testing and oral amoxicillin challenge in the outpatient allergy and clinical immunology clinic in penicillin-allergic pregnant women

Penicillin allergy is commonly reported. In pregnant women, reported penicillin allergy is associated with negative health outcomes and suboptimal group B streptococcal prophylaxis. For penicillin allergic individuals, skin testing followed by observed oral challenge is recommended. Prior data demonstrate a low risk of adverse reaction with skin testing in pregnant women, but subsequent oral challenge was not routinely pursued.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research