First experience with model-based selection of head and neck cancer patients for proton therapy

Compared to radiotherapy using photons, the superior beam properties of protons can be translated into two main strategies to obtain a clinical benefit: 1) dose escalation to improve local tumor control without increasing the risk of unacceptable radiation-induced toxicity, or 2) the sparing of healthy tissues with equivalent target dose to reduce the risk of radiation-induced side effects with similar tumor control. For the latter group of indications, the model-based approach was developed [1,2].

Source: Radiotherapy and Oncology - August 4, 2020 Category: Radiology Authors: Makbule Tambas, Roel J.H.M. Steenbakkers, Hans P. van der Laan, Atje M. Wolters, Roel G.J. Kierkels, Dan Scandurra, Erik W. Korevaar, Edwin Oldehinkel, Tineke W.H. van Zon-Meijer, Stefan Both, Johanna G.M. van den Hoek, Johannes A. Langendijk Tags: Original Article Source Type: research