Human Intestinal Parasitic Infection: A Narrative Review on Global Prevalence and Epidemiological Insights on Preventive, Therapeutic and Diagnostic Strategies for Future Perspectives.

Human Intestinal Parasitic Infection: A Narrative Review on Global Prevalence and Epidemiological Insights on Preventive, Therapeutic and Diagnostic Strategies for Future Perspectives. Expert Rev Gastroenterol Hepatol. 2020 Aug 05;: Authors: Wong LW, Ong KS, Khoo JR, Goh CBS, Hor JW, Lee SM Abstract INTRODUCTION: Intestinal parasitic infection (IPI) is a global health concern among socioeconomically deprived communities in many developing countries. Many preventative strategies have been deployed to control IPI, however, there is a lack in standards on the techniques used to diagnose and monitor the prevalence of IPI. AREAS COVERED: The present article will review the diseases associated with IPI and discuss the current IPI control strategies such as the water, sanitation, and hygiene (WASH) interventions, community-led total sanitation (CLTS) approach, and regular anthelminthic treatments. For the first time, this review will also evaluate all currently practised diagnostic techniques for the detection of intestinal parasites and provide insights on future IPI control strategies. EXPERT OPINION: Advanced and improved diagnostic methods such as qPCR coupled with a high-resolution melting curve, aptamers, biosensors and detection of extracellular vesicles can be used for detection of IPI. Vaccination against intestinal parasites can be made available to increase antibodies to interfere with the blood-feeding process by...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research