Procalcitonin as an antibiotic stewardship tool in COVID-19 patients in the intensive care
Publication date: September 2020Source: Journal of Global Antimicrobial Resistance, Volume 22Author(s): Lesley Heesom, Lucas Rehnberg, Myra Nasim-Mohi, Alexander I.R. Jackson, Michael Celinski, Ahilanadan Dushianthan, Paul Cook, William Rivinberg, Kordo Saeed
ConclusionsAfter the new national policy was implemented, the number of infection control professionals increased, and hand hygiene promotion activities were strengthened across Korean hospitals.
ConclusionsSBIs may occur in patients hospitalized with COVID-19 and lead to high mortality. The incidence of SBIs was associated with the severity of illness on admission. Gram-negative bacteria, especiallyA. baumannii andK. pneumoniae, were the main bacteria, and the resistance rates of the major isolated bacteria were generally high. This was a single-center study; thus, our results should be externally examined when applied in other institutions.
ConclusionsOur results illustrate the importance of continued adherence to infection prevention and control measures during the COVID-19 pandemic to prevent VRE transmission and healthcare associated infections.
Dr. Rodney Rohde, a virologist and clinical laboratory expert, explains how the Covid-19 pandemic can make antimicrobial resistance a bigger problem if health systems aren ’t careful.
Antimicrobial resistance ‘biggest human health threat, bar none’, says Australian research director ahead of three-year study in FijiThe emergence ofantimicrobial resistance (AMR), including drug-resistant bacteria, or “superbugs”, pose far greater risks to human health than Covid-19, threatening to put modern medicine “back into the dark ages”,an Australian scientist has warned, ahead of a three-year study into drug-resistant bacteria in Fiji.“If you thought Covid was bad, you don’t want anti-microbial resistance,” Dr Paul De Barro, biosecurity research director at Aus...
Publication date: December 2020Source: Journal of Global Antimicrobial Resistance, Volume 23Author(s): Jacopo Vannucci, Franco Ruberto, Daniele Diso, Gioacchino Galardo, Claudio M. Mastroianni, Giammarco Raponi, Massimiliano Bassi, Giancarlo Ceccarelli, Massimo Mancone, Guido Antonelli, Federico Venuta, Francesco Pugliese, Alida Albante, Francesco Alessandri, Davide Amore, Marco Anile, Maria Gloria Antognoli, Fabio Araimo Morselli, Daniela Auricchio, Martina Bianco
An amendment to this paper has been published and can be accessed via the original article.
Abstract Critical care medicine is a medical specialty engaging the diagnosis and treatment of critically ill patients who have or are likely to have life-threatening organ failure. Sepsis, a life-threatening condition that arises when the body responds to infection, is currently the major cause of death in intensive care units (ICU). Although progress has been made in understanding the pathophysiology of sepsis, many drawbacks in sepsis treatment remains unresolved. For example, antimicrobial resistance, controversial of glucocorticoids use, prolonged duration of ICU care and the subsequent high cost of the treat...
Purpose of review To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well as relevance of the COVID-19 pandemic in the potential increase of resistance. Recent findings Extended-spectrum and carbapenemase producing Enterobacterales and multidrug and extensive drug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii have increased worldwide. Sequence type (ST)131 Escherichia coli, ST258, ST11, ST10, ST147 and ST307 Klebsiella pneumonia...
ConclusionsHCWs need the support of the healthcare authorities not only to provide missing equipment, but also to communicate the risk to them. Conveying the information with full transparency, while addressing the uncertainty element and engaging the HCWs in evaluating the guidelines, are critical for establishing trust.