Impaired naming performance in temporal lobe epilepsy: language fMRI responses are modulated by disease characteristics

ConclusionsWhile frontal lobe language regions appear spared, temporal lobe language areas are susceptible to dysfunction and reorganisation, particularly in left TLE. Early onset and long duration of epilepsy, and high seizure frequency, were associated with compromised activation and deactivation patterns of task-associated regions, which might account for impaired naming performance in individuals with TLE.

Source: Journal of Neurology - August 2, 2020 Category: Neurology Source Type: research