GSE146402 Characterization of an Enzalutamide Resistant Primary Prostate Cancer Xenograft Derived from a Patient of West African Ancestry

Contributors : Brendon M Patierno ; Wen-Chi Foo ; Tyler Allen ; Jason A Somarelli ; Kathryn E Ware ; Santosh Gupta ; Sandra Wise ; John P Wise ; Xiaodi Qin ; Dadong Zhang ; Lingfan Xu ; Yanjing Li ; Xufeng Chen ; Brant A Inman ; Shannon J McCall ; Jiaoti Huang ; Rick A Kittles ; Kouros Owzar ; Simon Gregory ; Andrew J Armstrong ; Daniel J George ; Steven R Patierno ; David S Hsu ; Jennifer A FreedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHere we report the establishment and characterization of a Prostate Cancer Patient Derived Explant (PCPDX) from a patient of West African ancestry with metastatic castration resistant disease. The following data represents gene expression in a series of mice carrying this PCPDX and undergoing different treatment courses. Mice were treated for 10 weeks with either Enzalutamide, Cisplatin, or Docetaxel, or appropriate vehicle controls.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research