The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination

Chondroitin sulfate proteoglycans (CSPGs) are potent inhibitors of axonal regrowth and remyelination. More recently, they have also been highlighted as a modulator of macrophage infiltration into the central n...

Source: Journal of Neuroinflammation - July 23, 2020 Category: Neurology Authors: Annie Pu, Manoj K. Mishra, Yifei Dong, Samira Ghorbanigazar, Erin L. Stephenson, Khalil S. Rawji, Claudia Silva, Hiroshi Kitagawa, Stephen Sawcer and V. Wee Yong Tags: Research Source Type: research