Vulnerability of sickle cell disease persons to the COVID-19 in sub-Saharan Africa.

Vulnerability of sickle cell disease persons to the COVID-19 in sub-Saharan Africa. Hematology. 2020 Dec;25(1):280-282 Authors: Tonen-Wolyec S, Marini Djang'eing'a R, Kambale-Kombi P, Tshilumba CK, Bélec L, Batina-Agasa S PMID: 32657260 [PubMed - in process]
Source: Hematology - Category: Hematology Tags: Hematology Source Type: research

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This article focuses on the impact of the COVID-19 pandemic on child health in sub-Saharan Africa. We review the epidemiology of major pediatric diseases and, referencing modeling projections, discuss the short- and long-term impact of the pandemic on major disease control. We deliberate on potential complications of SARS-CoV-2 co-infections/co-morbidities and identify critical social and ethical issues. Furthermore, we highlight the paucity of COVID-19 data and clinical trials in this region and the lack of child participants in ongoing studies. Lastly, approaches and interventions to mitigate the pandemic's impact on chi...
Source: Pediatric Research - Category: Pediatrics Authors: Tags: Pediatr Res Source Type: research
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Short Communication Source Type: research
Authors: Noun P, Ibrahim A, Hodroj MH, Bou-Fakhredin R, Taher AT Abstract INTRODUCTION: Many patients with inherited or acquired benign hematological disorders are at increased risk of developing severe complications from COVID-19. These patients, therefore, require specific advice regarding isolation and changes to their usual treatment schedules. Their disease can also be associated with significant burden, and they necessitate life-long and regular access to therapy, and regular follow-up consultations and hospital visits. The current COVID-19 pandemic is therefore presenting many challenges for these patients, ...
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
PMID: 32815179 [PubMed - as supplied by publisher]
Source: Transfusion - Category: Hematology Authors: Tags: Transfusion Source Type: research
Did you know that the NIH’s small business programs (SBIR and STTR) invest over 1 billion dollars into life science and healthcare companies each year? The newly-created Small business Education and Entrepreneurial Development (SEED) office provides grantees with many of the valuable entrepreneurship and commercialization services we have discussed in previous blogs to help them thrive. As our small business program has grown, we have seen early ideas transform into improved patient access to technologies. To celebrate these successes, the NIH has launched a new interactive mapping tool thatfeatures many of the a...
Source: NIH Extramural Nexus - Category: Research Authors: Tags: blog Open Mike SBIR small business Source Type: funding
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Source: Hemoglobin - Category: Hematology Authors: Source Type: research
A 35-year-old man with sickle-cell trait and diabetes who had undergone renal transplantation presented with weeks of episodic severe cramping, abdominal pain, diarrhea, maroon stool, and anorexia despite using empiric antibiotics for gastroenteritis. At presentation, his laboratory results noted a mild leukocytosis and a hemoglobin of 6.4 g/dL. Real-time polymerase chain reaction of a nasopharyngeal sample gave a positive result for SARS-CoV-2 despite the lack of respiratory symptoms or fever. A CT scan demonstrated diffusely thickening of the stomach and small-bowel walls (A).
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: At the focal point Source Type: research
COVID-19 can cause severe inflammation and lung injury. And that can have a greater impact on people with sickle cell disease, a group of inherited red blood cell disorders.
Source: WebMD Health - Category: Consumer Health News Source Type: news
MONDAY, July 13, 2020 -- People with sickle cell disease are at increased risk for severe complications from COVID-19, an expert says. " Many patients experience a pain crisis, also known as a vaso-occlusive crisis, early in COVID-19 infection...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
J. A. Panepinto et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
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