Enzymatic degradation of liquid droplets of DNA is modulated near the phase boundary [Biophysics and Computational Biology]

Biomolecules can undergo liquid–liquid phase separation (LLPS), forming dense droplets that are increasingly understood to be important for cellular function. Analogous systems are studied as early-life compartmentalization mechanisms, for applications as protocells, or as drug-delivery vehicles. In many of these situations, interactions between the droplet and enzymatic solutes are important...

Source: Proceedings of the National Academy of Sciences - July 13, 2020 Category: Science Authors: Omar A. Saleh, Byoung-jin Jeon, Tim Liedl Tags: Physical Sciences Source Type: research