Preparation of Labeled Aromatic Amino Acids via Late-Stage 18F-Fluorination of Chiral Nickel and Copper Complexes

Chem. Commun., 2020, Accepted Manuscript DOI: 10.1039/D0CC02223C, CommunicationAustin Craig, Niklas Kolks, Elizaveta Alexandrovna Urusova, Johannes Zischler, Melanie Brugger, Heike Endepols, Bernd Neumaier, Boris D. Zlatopolskiy A general protocol for the preparation of18F-labeled AAAs and α-methyl-AAAs applying alcohol-enhanced Cu-mediated radiofluorination of Bpin-substituted chiral complexes using Ni/Cu-BPX templates as double protecting groups is reported. The chiral... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chem. Commun. latest articles - July 9, 2020 Category: Chemistry Authors: Austin Craig Source Type: research