New Swine Flu Poses Possible Pandemic Risk

The G4 virus is genetically descended from the H1N1 swine flu that caused a pandemic in 2009, CNN reported.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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AbstractThe global pandemic of coronavirus disease 2019 (COVID-19) has upended the world with over 6.6 million infections and over 391,000 deaths worldwide. Reverse-transcription polymerase chain reaction (RT-PCR) assay is the preferred method of diagnosis of COVID-19 infection. Yet, chest CT is often used in patients with known or suspected COVID-19 due to regional preferences, lack of availability of PCR assays, and false-negative PCR assays, as well as for monitoring of disease progression, complications, and treatment response. The International Atomic Energy Agency (IAEA) organized a webinar to discuss CT practice and...
Source: European Radiology - Category: Radiology Source Type: research
TWiV reviews a new H1N1 swine influenza virus from China with pandemic potential, Ad5 vectored SARS-CoV-2 oral vaccine candidate, Operation Warp Speed vaccine candidates, FDA guidance on vaccine approval, and answer listener email. Click arrow to playDownload TWiV 634 (72 MB .mp3, 120 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology adenovirus COVID-19 FDA vaccine guidance Operation Warp Speed SARS-CoV-2 viral viruses Source Type: blogs
Abstract World has been suffering from pandemic caused by mysterious Coronavirus. The novel member of Coronaviridae causing COVID-19 disease is named as SARS-Cov-2. Its first case was reported in China by the end of 2019, but its exponential spread has wrapped entire globe, suspended and is penalizing mankind. A retrospective meta-analysis study showed that outbreaks of Middle East Respiratory Syndrome (MERS) and SARS-Cov-1 (Coronaviridae), influenza infection H1N1 and West-African Ebola caused lower mortality than this new pandemic COVID-19. Virus has appeared as a new human pathogen so to counter COVID-19 no spe...
Source: Acta Microbiologica et Immunologica Hungarica - Category: Microbiology Authors: Tags: Acta Microbiol Immunol Hung Source Type: research
Chinese researchers have discovered a new type of virus in pigs that can infect humans and is capable of causing a pandemic, according to a new study. The disease, which researchers called the G4 virus, is genetically descended from the H1N1 swine flu.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
A new study warns that the strain of H1N1, common on China ’s pig farms since 2016, should be “urgently” controlled to avoid another pandemic.
Source: NYT Health - Category: Consumer Health News Authors: Tags: China Pigs Swine Influenza Proceedings of the National Academy of Sciences Source Type: news
G4 strain has already infected 10% of industry ’s workers in China but no evidence yet that it can be passed from human to humanResearchers in China have discovered a new type of swine flu that is capable of triggering a pandemic, according to a study in the US science journal PNAS, although experts said there is no imminent threat.Named G4, it is genetically descended from the H1N1 strain that caused a pandemic in 2009.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Swine flu World news Health China Infectious diseases Science Source Type: news
Pandemic influenza A viruses can emerge from swine, an intermediate host that supports adaptation of human-preferred receptor-binding specificity by the hemagglutinin (HA) surface antigen. Other HA traits necessary for pandemic potential are poorly understood. For swine influenza viruses isolated in 2009 –2016, gamma-clade viruses had less stable HA proteins (activation pH 5.5–5.9) than pandemic clade (pH 5.0–5.5). Gamma-clade viruses replicated to higher levels in mammalian cells than pandemic clade. In ferrets, a model for human adaptation, a relatively stable HA protein (pH 5.5–5.6) was n ecessar...
Source: eLife - Category: Biomedical Science Tags: Microbiology and Infectious Disease Source Type: research
CONCLUSIONS: Our study of influenza in a cohort of otherwise healthy, outpatient adult Department of Defense beneficiaries over 5 influenza seasons revealed few differences between influenza A(H1N1), influenza A(H3N2), and influenza B infection with respect to self-reported disease severity or clinical outcomes. This study highlights the importance of routine, active, and laboratory-based surveillance to monitor ongoing trends and severity of influenza in various populations to inform prevention measures. PMID: 32588899 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
Developing a SARS-CoV-2 vaccine and distribution plan is an'insurmountable task'but can be done with timely planning that builds on lessons learned during the 2009 H1N1 influenza pandemic.Medscape Medical News
Source: Medscape Pharmacist Headlines - Category: Drugs & Pharmacology Tags: Infectious Diseases News Source Type: news
Sentinel surveillance of acute hospitalisations in response to infectious disease emergencies such as the 2009 influenza A(H1N1)pdm09 pandemic is well described, but recognition of its potential to supplement routine public health surveillance and provide scalability for emergency responses has been limited. We summarise the achievements of two national paediatric hospital surveillance networks relevant to vaccine programmes and emerging infectious diseases in Canada (Canadian Immunization Monitoring Program Active; IMPACT from 1991) and Australia (Paediatric Active Enhanced Disease Surveillance; PAEDS from 2007) and discu...
Source: Eurosurveillance - Category: Infectious Diseases Authors: Source Type: research
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