Risk Factors for Fibromyalgia and Chronic Widespread Pain Risk Factors for Fibromyalgia and Chronic Widespread Pain

This review demonstrates a wide variety of risk factors for fibromyalgia, strongly suggesting that there are multiple etiological routes into fibromyalgia and chronic widespread pain.Pain
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

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Noninvasive measures of neuroinflammatory processes in humans could substantially aid diagnosis and therapeutic development for many disorders, including chronic pain. Several proton magnetic resonance spectroscopy (1H-MRS) metabolites have been linked with glial activity (ie, choline and myo-inositol) and found to be altered in chronic pain patients, but their role in the neuroinflammatory cascade is not well known. Our multimodal study evaluated resting functional magnetic resonance imaging connectivity and 1H-MRS metabolite concentration in insula cortex in 43 patients suffering from fibromyalgia, a chronic centralized ...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
García Martínez-Rodríguez Fibromyalgia is a condition characterised by chronic widespread muscle pain and fatigue, sleep disturbances, cognitive disorders, and mood disturbance. The purpose of this study was to determine the effectiveness of a manual therapy technique performed with moderate digital pressure in women with fibromyalgia (n = 24). In this randomised, controlled trial, the participants were randomly assigned to the experimental group or placebo group. The experimental group was assisted with manual therapy sessions based on connective tissue massage, whereas the placebo group was &a...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Despite the current efforts to manage cancer pain with opioids, a significant number of cancer patients still experience pain. One reason may be that such patients have pain that comes from problems with the brain ’s processing of pain rather than nociception, neuropathy, or inflammation. Pain related to aberrant central nervous system processing is called “central pain.” Central pain is the key pathway in many chronic pain syndromes (e.g. fibromyalgia).
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
Authors: Overholt TL, Evans RJ, Lessey BA, Matthews CA, Hines KN, Badlani G, Walker SJ Abstract INTRODUCTION: Interstitial cystitis/bladder pain syndrome (IC/BPS) and endometriosis are coexistent diagnoses in 48%-65% of women with chronic pelvic pain (CPP), suggesting that dual screening may be warranted. To further investigate the clinical relationship and risk factors between these two conditions, we performed a retrospective review of our large IC/BPS patient data registry. MATERIALS AND METHODS: We evaluated IC/BPS patients who were prospectively enrolled into our registry who completed validated questionna...
Source: Canadian Journal of Urology - Category: Urology & Nephrology Tags: Can J Urol Source Type: research
Conclusions The increased anandamide and decreased SEA in women with FM after the 15-wk program might point to a chronic effect of resistance exercise. Pain and depression scorings decreased in the FM group after the program, but no associations between pain, depression, and lipid level changes were assured.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
AbstractOver 60% of rheumatoid arthritis (RA) patients achieve a good response after 12  months of treatment when following the European league against rheumatism (EULAR) guidelines for treatment. However, almost half of patients still suffer from moderate to severe disease activity despite this. In addition, mental health problems may remain despite reduced measures of inflammation s ystemically and within joints. Depression is two times more common in RA patients than in the general population, and intriguingly a bi-directional relationship with RA has been shown in cross-sectional studies. Chronic inflammation impa...
Source: Rheumatology and Therapy - Category: Rheumatology Source Type: research
ConclusionsWhole-body cryotherapy is a useful method to improve standard pharmacological treatment. The WBC intervention reduces mental health deterioration, especially in mood disorders, such as depression, and can be beneficial for well-being and quality of life.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Discussion: Normal levels of pressure pain tolerance at baseline predicted greater improvement in clinical pain severity after EAET than CBT. Quantitative sensory testing may provide insights about individual responses to psychologically based therapies for individuals with chronic pain.
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research
Fibromyalgia is a chronic, widespread pain syndrome, with unclear etiology, characterized by fatigue, sleeping problems, cognitive disorders, somatic complaints and severe pain in tender points of the body at the time of physical activity with no laboratory findings to the disease and diagnostic tests. Fibromyalgia can be associated with ocular symptoms (foreign body sensation, irritation) and visual disturbances (blurred vision), coexisting with dry eye syndrome (DES) and reduced corneal sensitivity.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Major review Source Type: research
Chronic widespread pain (CWP) is a complex pain condition characterized by generalized musculoskeletal pain and often associated with other symptoms. An important clinical feature is widespread increased pain sensitivity such as lowered pain thresholds for mechanical stimuli (pressure pain thresholds [PPT]). There is a growing interest in investigating the activated neurobiological mechanisms in CWP, which includes fibromyalgia. In CWP, strong significant correlations have been found between muscle protein patterns and PPT. This explorative proteomic study investigates the multivariate correlation pattern between plasma pr...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
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