TP53 p.Arg337His geographic distribution correlates with adrenocortical tumor occurrence

ConclusionWe presented for the first time the p.Arg337His frequency among individuals unselected for any disease from a subset of the S ão Paulo State, the most populous in Brazil. The allele discrimination assay we presented here has proven to be a reliable and efficient method for high‐throughput genotyping. ACT was found to be a good sentinel cancer to suppose p.Arg337His presence in our region.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research