Interaction of irritability and anxiety on emotional responding and emotion regulation: a functional MRI study.
CONCLUSIONS: Atypical maintenance of emotional stimuli within the rostro-medial prefrontal cortex may exacerbate the difficulties faced by adolescents with irritability. Moreover, increased anxiety combined with significant irritability may disrupt an automatic emotional conflict-based form of emotion regulation that is particularly associated with the ventral anterior cingulate cortex.
PMID: 32584213 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Crum KI, Hwang S, Blair KS, Aloi JM, Meffert H, White SF, Tyler PM, Leibenluft E, Pope K, Blair RJR Tags: Psychol Med Source Type: research