30. Curation of genetic variants in childhood cancers within the Clinical Genome Resource (ClinGen)

The Clinical Genome Resource (ClinGen) Somatic Cancer Clinical Domain Working Group (CDWG) (https://www.clinicalgenome.org/working-groups/somatic/) is a multi-institution team engaged in developing processes and resources to provide accurate curation and classification of somatic variants in cancer. While most knowledgebases provide information on variants in adult malignancies, alterations in pediatric cancers, which are fundamentally different, are rarely discussed.

Source: Cancer Genetics and Cytogenetics - May 31, 2020 Category: Genetics & Stem Cells Authors: Wan-Hsin Lin, Angshumoy Roy, Alanna Church, Shruti Rao, Deborah Ritter, Arpad Danos, Kilannin Krysiak, Laura Corson, Kevin Fisher, Heather Williams, Matthew Hiemenz, Katherine Janeway, Jianling Ji, Chimene Kesserwan, Theodore Laetsch, Donald Parsons, Ryan Source Type: research