388 Natural history and management of basal cell nevus syndrome: Updates from the gorlin syndrome registry

Background: Patients with basal cell nevus syndrome (BCNS) are at increased risk of developing basal cell carcinomas (BCCs). Long-term data on tumor burden, co-morbidities, and management of BCNS is limited. Method: A prospective, cross-sectional study of self-reported questionnaire responses collected from BCNS patients from Feb 2012 to Oct 2016 through the national Gorlin Syndrome Registry. BCC burden was characterized based on frequency and anatomic distribution. Logistic regression analysis was performed to determine the association of BCC development with risk factors such as sex, family history, age of diagnosis/symptoms, and sun exposure.

Source: Journal of Investigative Dermatology - June 17, 2020 Category: Dermatology Authors: V. Eng, G. Saldanha, S. Li, I. Bailey-Healy, J. Teng, J. Tang Tags: Patient Population Research Source Type: research