Syntheses of α-CF3-α-quaternary ketones via p-quinone methides and their derivatization to compounds with successively congested stereogenic centers

Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00951B, PaperKyu Terashima, Tomoko Kawasaki-Takasuka, Tomohiro Agou, Toshio Kubota, Takashi Yamazaki NHC-catalyzed 1,6-conjugate additions of a variety of aldehydes to δ-CF3- δ-substitutedp-quinone methides and their highly diastereoselective derivatization to compounds with successively congested stereogenic centers were performed. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - June 10, 2020 Category: Molecular Biology Authors: Kyu Terashima Source Type: research