Efficient and selective antibody modification with functionalised divinyltriazines

This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Andrew James Counsell, Stephen J Walsh, Naomi Stephanie Robertson, Hannah Sore, David R Spring A highly efficient disulfide rebridging strategy for the modification of monoclonal antibodies with substituted divinyltriazine linkers is reported. The reaction proceeds efficiently under mild conditions with near stoichiometric quantities of... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research