Dosimetric comparison of inverse and forward planning for Gamma Knife stereotactic radiosurgery of brain metastases

The Leksell GammaPlan (LGP) with an inverse planning (IP) tool has been upgraded to version 11.1 since its launch in 2010. We evaluated its IP planning performance by re-planning 16 targets that had been planned using forward planning (FP). The FP and IP plans were compared. A planning guideline for IP process was developed aiming for an unbiased comparison. Sixteen brain metastases (BMs) without nearby critical structures were included in the study (size> 1 cm for all targets). All prior FP were re-planned in the LGP using IP and maintaining the same beam-on time and coverage.

Source: Medical Dosimetry - June 6, 2020 Category: Radiology Authors: Qianyi Xu, Dershan Luo, David Mulvihill, Warren Goldman, Alan Turtz, Gregory J. Kubicek Source Type: research