Trends of nanotechnology in type 2 diabetes mellitus treatment

Publication date: Available online 4 June 2020Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Yannis V. Simos, Konstantinos Spyrou, Michaela Patila, Niki Karouta, Haralambos Stamatis, Dimitrios Gournis, Evangelia Dounousi, Dimitrios Peschos
Source: Asian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research

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This study used 30 adult male mice strain BALB/c. Diabetes was induced using high-fat diet/streptozotocin method until random blood glucose level reached> 200 mg/dL. Diabetic mice were then exposed to electrical field (static and dynamic), magnetic field (static and induce), and infrared ray (with or without infrared ray) combination therapy 15 min daily for 28 days. Fasting blood glucose level, plasma insulin level, HOMA-IR index, and membrane GLUT-4 density after treatment were analyzed statistically atα = 0.05. Result showed that exposure combination of electrical field, magnetic field, and infrared were found ...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
The objective of this study was investigating the additional effect of DL with nonsurgical periodontal treatment on the red complex bacteria in type 2 diabetes mellitus (DM) patients with chronic periodontitis (CP). Sixty type 2 DM patients with chronic periodontitis (CP) were randomly assigned in two parallel groups to receive scaling root planning (SRP,n = 30) or SRP followed by DL periodontal pocket irradiation (SRP + DL,n = 30). Recording of clinical parameters and subgingival plaque sampling were performed at baseline, and post therapy (1 and 3 months after treatment). Amounts ofPorphy...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Publication date: Available online 10 July 2020Source: Canadian Journal of DiabetesAuthor(s): Yun-Ru Lai, Chih-Cheng Huang, Hsueh-Wen Chang, Wen-Chan Chiu, Nai-Wen Tsai, Ben-Chung Cheng, Jung-Fu Chen, Cheng-Hsien Lu
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Authors: Díaz-Cerezo S, Romera I, Sicras-Mainar A, López-Simarro F, Dilla T, Artime E, Reviriego J Abstract Objective: To compare healthcare resource use (HRU) and annual costs in type 2 diabetes mellitus (T2DM) patients with poor glycaemic control and obesity versus good glycaemic control without obesity.Methods: Observational retrospective study based on the analysis of electronic medical records from the BIG-PAC database, with one year of follow-up. T2DM patients aged ≥30 years who requested medical care during 2013 were included. Annual HRU and costs per patient were compared between a referenc...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
The use of Complementary and Alternative Medicine (CAM) among Type 2 Diabetes Mellitus (T2DM) patients is increasing to manage the complexities of their condition, enhance their health, and ease complications....
Source: BMC Complementary and Alternative Medicine - Category: Complementary Medicine Authors: Tags: Research article Source Type: research
The novel coronavirus disease (COVID-19) has been on the rampage ever since its outbreak in December 2019 in Wuhan, China. To date, the disease has affected over 5.3 million people, inflicting more than 342,000 casualties in over 200 nations worldwide [1]. Although the overall mortality rate of COVID-19 ranges from 1.4 to 7.2% [2,3], patients with underlying co-morbidities like diabetes mellitus (DM) tend to have severe disease, acute respiratory distress syndrome (ARDS) and increased mortality [4,5], People with both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are at a high risk of poor outcomes with COVID-19 [6].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
AbstractIntroductionA second-generation basal insulin analogue insulin glargine 300  U/mL (Gla-300) has been marketed in France since June 2016. This real-world study was designed to assess persistence with Gla-300 and the prevalence of related hypoglycemia requiring hospitalization as compared to first-generation basal insulins, in patients with type 2 diabetes mellitus (T2DM).MethodsA retrospective study was conducted using data in the large French comprehensive national healthcare system claims databases. Patients with T2DM newly treated with insulin in 2016 and 2017 (2-year period) were included. Three basal insul...
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
Misfolding and extracellular deposition of proteins is the hallmark of a heterogeneous group of conditions collectively termed protein misfolding and deposition diseases or amyloidoses. These include both localized (e.g. Alzheimer’s disease, prion diseases, type 2 diabetes mellitus) and systemic amyloidoses. Historically regarded as a group of maladies with limited, even inexistent, therapeutic options, some forms of systemic amyloidoses have recently witnessed a series of unparalleled therapeutic successes, positively impacting on their natural history and sometimes even on their incidence. In this review article we...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion: Our findings reported metformin as the most commonly prescribed antihyperglycemic agent, sodium glucose linked transporter-2 (SGLT-2) inhibitor being under-prescribed, and detected poorly controlled diabetes in majority of patients with T2DM and HF. Understanding the prescribing pattern of antihyperglycemic agents supports the implementation of evidence-based treatment in HF patients with T2DM to improve patients' outcomes.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Publication date: September–October 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 14, Issue 5Author(s): Midhuna K, Prashant S. Adole, Kolar V. Vinod, N. Balamurugan
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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