Increased responding for alcohol and resistance to aversion in female mice.

CONCLUSIONS: Females respond more for EtOH at higher concentrations and continue to respond for 10% EtOH at all concentrations of quinine, suggesting that female mice are more motivated to respond for alcohol in an operant self-administration paradigm than males. Understanding behavioral and mechanistic sex differences in responding for alcohol will allow for the advancement of treatments for women with AUD.
PMID: 32472651 [PubMed - as supplied by publisher]

Source: Alcoholism, Clinical and Experimental Research - May 28, 2020 Category: Addiction Authors: Sneddon EA, Ramsey OR, Thomas A, Radke AK Tags: Alcohol Clin Exp Res Source Type: research