The effect of morbid obesity or advanced maternal age on oxytocin-induced myometrial contractions: an in vitro study

ConclusionsOxytocin pre-treatment reduced myometrial contractility in AMA and control group women compared with their oxytocin-na ïve counterparts, as a function of the desensitization phenomenon. Attenuated oxytocin-induced myometrial contractility in MO women in both oxytocin-pretreated and oxytocin-naïve samples suggests that these women have intrinsically reduced uterine contractile ability.Trial registrationwww.clinicaltrials.gov (NCT01865669; registered 28 May, 2013).
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research