P(NMe2)3 mediated cyclopropanation of α-methylene-β-lactams for rapid syntheses of spirocyclopropyl β-lactams

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00826E, PaperSi-qin Luo, Wei Liu, Banfeng Ruan, Shilu Fan, Huixia Zhu, Wei Tao, Hua Xiao An expedient cyclopropanation of α-methylene-β-lactams with α-keto esters mediated by P(NMe2)3 has been developed. This reaction enables rapid access to a series of functionalized spirocyclopropyl β-lactams in good yields from... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research