Atypical clinical presentation of Ebola virus disease in pregnancy: Implications for clinical and public health management

Between December 2013 and June 2016, West Africa experienced the largest outbreak of Ebola virus disease (EVD) in history, with at least 28,646 cases and 11,323 deaths.(WHO, 2019) Prior to this outbreak, the small number (2,345) of cumulative cases of EVD meant that relatively little was known about the clinical course of EVD,(CDC, 2019) especially in pregnant women. Few reports describe the clinical outcomes in pregnant women infected with EVD, and their newborns.(Piot et al., 1978; World Health and Organization, 1978; Bwaka et al., 1999; Mupapa et al., 1999; Caluwaerts et al., 2016; Baize et al., 2014; Caluwaerts, 2017; Caluwaerts et al., 2018; Chiu et al., 2018; Henwood et al., 2017; Lyman et al., 2018; Mpofu et al., 2019; Nelson et al., 2016; Oduyebo et al., 2015; UNFPA, 2020) Previous reports largely described pregnant women with EVD who presented with typical symptoms, spontaneous abortion,(World Health and Organization, 1978; Bwaka et al., 1999; Mupapa et al., 1999; Baize et al., 2014; Henwood et al., 2017; Lyman et al., 2018; Mpofu et al., 2019; Baggi et al., 2014; Chertow et al., 2014; Schieffelin et al., 2014) pregnancy-related hemorrhage,(Mupapa et al., 1999; Caluwaerts et al., 2016; Caluwaerts, 2017; Henwood et al., 2017; Lyman et al., 2018; Mpofu et al., 2019; Schieffelin et al., 2014) and stillbirth.(Mupapa et al., 1999; Caluwaerts et al., 2016; Henwood et al., 2017; Lyman et al., 2018; Mpofu et al., 2019; Oduyebo et al., 2015; Baggi et al., 2014) While mortalit...
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research