Efficacy and safety of duloxetine in osteoarthritis or chronic low back pain? The tip of an iceberg!

Weng and colleagues must be commended for their attempts to clarify the benefit/harm ratio of duloxetine in osteoarthritis and chronic low back pain1. Indeed, the high number of therapeutic options available shows the state of affairs is a lottery while these frequent conditions “associated with substantial work disability, morbidity, costs, and increased mortality rates” deserve robust evidence2. However, their conclusion “Duloxetine had modest to moderate effects… with mild adverse events” claiming “future randomized controlled trials should focus on comparing duloxetine…” deserves scrutiny.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Tags: Letter to the Editor Source Type: research