The impact of the effective dose to immune cells on lymphopenia and survival of esophageal cancer after chemoradiotherapy: Asian perspectives in the immunotherapy era

To the Editor: We read the work by Xu, et al [1] with great interest and congratulate them for the publication of this large-scale retrospective study. Radiation-induced lymphopenia is an important prognostic factor for esophageal cancers [2,3] and many other solid tumours [4]. The estimation of dose to circulating lymphocytes by adopting the effective dose to immune cells (EDIC) formula is gaining external validity in different types of cancers. In stage III non-small cell lung cancer, Ladbury, et al [5] have recently published the correlation of EDIC and lymphopenia with consistent findings.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research