Spraying vitamin C solution for relief of mucosal irritation caused by Lugol chromoendoscopy

We read with great interest the recent study by Jin et  al,1 in which they evaluated the safety and efficacy of vitamin C solution (VCS) for relieving adverse symptoms caused by Lugol iodine staining. A previous study verified the feasibility and usefulness of 5% sodium thiosulfate solution (STS).2 This multicenter, randomized, double-blind study ini tially compared normal saline solution (NS), STS, and 2% VCS after spraying Lugol iodine solution to evaluate the acute and late adverse symptoms and the discoloration effect on esophageal mucosa stained brown by iodine.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research