Coronavirus disease 2019 outbreak: liver disease a prognostic tool?

Coronavirus disease 2019 outbreak: liver disease a prognostic tool? Panminerva Med. 2020 May 14;: Authors: Testino G, Fagoonee S PMID: 32414233 [PubMed - as supplied by publisher]
Source: Panminerva Medica - Category: General Medicine Tags: Panminerva Med Source Type: research

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on March 11, 2020 the World Health Organization (WHO) declared Coronavirus disease 2019 (COVID-19) a pandemic.1 Worldwide, clinicians of all specialties started to deal with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) and most of the efforts have been focused on the fight against this enemy. However, other diseases have not stopped to affect our patients and we confronted with the difficulties to provide the best care to patients with gastrointestinal diseases during this pandemic.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Correspondence Source Type: research
Authors: Konturek PC, Harsch IA, Neurath MF, Zopf Y Abstract Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV2) outbreak is the most dramatic event since World War II. Originating as a cluster of unexplained cases of pneumonia, it turned out that this viral disease termed COVID-19 is not only a respiratory infection, but a systemic disease associated with a number of extrapulmonary complications. One of the medical disciplines that is strongly affected by this viral infection is gastroenterology. COVID-19 causes in some patients typical symptoms of enteritis such as diarrhea or abdominal pain. There is als...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
In the first months of 2020 the world faced a viral respiratory disease outbreak related to coronavirus SARS-CoV-2, which was declared a pandemic by the World Health Organization (WHO) on March 31st. To date nearly 4 million cases have been documented and a quarter of a million deaths reported globally.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Correspondence Source Type: research
Authors: Casella G, Ingravalle F, Ingravalle A, Monti C, Bonetti F, Limonta A Abstract The outbreak of Coronavirus Disease 2019 (COVID-19) worldwide had evidenced the opportunity to increase the interaction between Specialist and Primary Care Physician (PCP). COVID 19, started in December 2019 in China, has been considered a public health emergency by the Department of Health and Human Services and, at the moment, it is a pandemic disease with worldwide diffusion. The Covid 19 crisis permits to increase the role of Telemedicine as a tool for the delivery of health care services at distance and to slow down the viru...
Source: Minerva Gastroenterologica e Dietologica - Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research
Abstract The outbreak of coronavirus disease 2019 (COVID-19) starting last December in China placed emphasis on liver involvement during infection. This review discusses the underlying mechanisms linking COVID-19 to liver dysfunction, according to recent available information, while waiting further studies. The manifestations of liver damage are usually mild (moderately elevated serum aspartate aminotransferase activities), and generally asymptomatic. Few patients can still develop severe liver problems, and therapeutic options can be limited. Liver dysfunction may affect about one-third of the patients, with prev...
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Eur J Intern Med Source Type: research
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible application as a treatment modality for SARS-CoV-2 patients. COVID-19 patients develop severe hypoxemia early in the course of the disease, which is silent most of the time. Small fibrinous thrombi in pulmonary arterioles and a tumefaction of endothelial were observed in the autopsies of fatal COVID-19 cases. Studies showed...
Source: Clinics - Category: General Medicine Source Type: research
It is with great interest that I read the publication of F. Zingone et al. recommending screening for active coronavirus disease 2019 infection (CoVID-19) and immunization status prior to biologic therapy in inflammatory bowel disease (IBD) patients at the time of the pandemic outbreak [1]. As the authors suggest, the screening of CoVID-19 positive cases is mandatory in the management of IBD patients even when presenting symptoms are exclusively digestive. However, the screening should not be limited to swab or throat samples.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Correspondence Source Type: research
First appearing in Wuhan, China, the coronavirus disease of 2019 (COVID-19) is caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV2) [1,2]. Given the rapid spread of this virus with consequences on an international scale, COVID-19 was declared a pandemic by the World Health
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Digestive Endoscopy Source Type: research
During the pandemic caused by the novel Coronavirus SARS-CoV-2 disease (COVID-19) questions arise on risk of patients with autoimmune conditions under immunosuppressive drugs (IS). There is a mounting evidence that severe COVID-19 is characterized by an imbalanced multi-system immune-inflammatory response to the pathogen by the host, and acknowledged risk factors for poorer outcome are older age and preexisting non-respiratory chronic pro-inflammatory conditions such as obesity, hypertension, diabetes and cardiovascular disease (1).
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
One of the worst symptoms of any plague is uncertainty—who it will strike, when it will end, why it began. Merely understanding a pandemic does not stop it, but an informed public can help curb its impact and slow its spread. It can also provide a certain ease of mind in a decidedly uneasy time. Here are some of the most frequently asked questions about the COVID-19 pandemic from TIME’s readers, along with the best and most current answers science can provide. A note about our sourcing: While there are many, many studies underway investigating COVID-19 and SARS-CoV-19, the novel coronavirus that causes the illn...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Explainer Source Type: news
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