Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model
Conclusions: Treatment with an A2BAdoR antagonist at 1 week results in the improvement in cardiac function and decreased substrate for VT. The inhibition of fibrogenesis by A2BAdoR antagonists may be a new target for the prevention of adverse remodeling after MI.
Source: Heart Rhythm - Category: Cardiology Authors: Hao Zhang, Hongyan Zhong, Thomas H. Everett, Emily Wilson, Roger Chang, Dewan Zeng, Luiz Belardinelli, Jeffrey E. Olgin Tags: Experimental Source Type: research