Dosimetric and radiobiological comparison of simultaneous integrated boost and sequential boost of locally advanced cervical cancer

According to international recommendations by GEC-ESTRO GYN working group [1], combined radiation therapy is the most effective treatment for locally advanced cervical cancer (LACC). Classical combined radiotherapy includes two sequential stages: external beam radiotherapy (EBRT) and brachytherapy (BT) [1]. EBRT is used for irradiation of the tumour itself and the lymph nodes to total dose values up to 50Gy. BT is used as a boost for irradiation of the tumour up to EQD2 doses as high as 90Gy. The golden standard of modern combined radiotherapy includes EBRT followed by image-guided adaptive BT.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research