Colchicine and Leukopenia: Clinical Implications

Colchicine is the mainstay of treatment for familial Mediterranean fever. We investigated the frequency of leukopenia in 213 patients with familial Mediterranean fever treated with standard doses of colchicine (0.5-2.0  mg/day). We found that 23 patients (10.8%) had reversible leukopenia, 3 moderate, and none severe and that their rate of infections was not increased.

Source: The Journal of Pediatrics - May 13, 2020 Category: Pediatrics Authors: Erdal Sag, Yagmur Bayindir, Aydin Adiguzel, Selcan Demir, Yelda Bilginer, Selin Aytac, Seza Ozen Tags: Brief Reports Source Type: research