IL-7 induces sCD127 release and mCD127 downregulation in human CD8+ T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection.

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Source: European Journal of Immunology - May 10, 2020 Category: Allergy & Immunology Authors: Côté SC, Schinkel SCB, Berthoud TK, Barros PO, Sanchez-Vidales M, Davidson AM, Crawley AM, Angel JB Tags: Eur J Immunol Source Type: research