Bimodal magnetic resonance and optical imaging of extracellular matrix remodelling by orthotopic ovarian tumours

British Journal of Cancer, Published online: 11 May 2020; doi:10.1038/s41416-020-0878-7Bimodal magnetic resonance and optical imaging of extracellular matrix remodelling by orthotopic ovarian tumours
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research

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Contributor : Oliver DorigoSeries Type : Expression profiling by arrayOrganism : Mus musculusWe used mouse Clariom-S microarrays to study the gene expression profile of ID8 cancer cells stimulated with C-C Chemokine Ligand 6 (CCL6).
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
Publication date: Available online 3 July 2020Source: Journal of Trace Elements in Medicine and BiologyAuthor(s): B. Toubhans, A.T Gourlan, P. Telouk, K. Lutchman-Singh, L.W. Francis, R.S. Conlan, L. Margarit, D. Gonzalez, L. Charlet
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
Cancers, Vol. 12, Pages 1801: Role of Curcumin and (−)-Epigallocatechin-3-O-Gallate in Bladder Cancer Treatment: A Review Cancers doi: 10.3390/cancers12071801 Authors: Ludwika Piwowarczyk Maciej Stawny Dariusz T. Mlynarczyk Izabela Muszalska-Kolos Tomasz Goslinski Anna Jelińska The incidence of bladder cancer (BC) is increasing, and although current therapeutic approaches are effective in many cases, recurrence of BC is common. Therefore, it seems necessary to search not only for novel therapeutic approaches, but also for new therapeutic agents. Natural polyphenols, such as curcumin (CUR) and epiga...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Contributors : Fangfang Song ; Baifeng ZhangSeries Type : Expression profiling by arrayOrganism : Homo sapiensAltered methylation patterns in HGSOC were further characterized by gene expression profiles. By integrating DNA methylation and mRNA expression data, we identified genes with negative and positive correlation, aiming to identify molecular drivers and pathways that are HGSOC-related.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
The purpose of this study was to explore the efficacy and tolerability of poly ADP-ribose polymerase (PARP) inhibitors in patients with ovarian cancer.
Source: World Journal of Surgical Oncology - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Publication date: Available online 3 July 2020Source: Clinica Chimica ActaAuthor(s): Boddapati Kalyani Bhardwaj, Sanu Thankachan, Thejaswini Venkatesh, Padmanaban S. Suresh
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Conclusions: Operative laparoscopy under conscious sedation and local anesthesia appears to be a feasible technique in gynecologic surgery with no adverse patient outcomes. PMID: 32612345 [PubMed - in process]
Source: JSLS : Journal of the Society of Laparoendoscopic Surgeons - Category: Surgery Tags: JSLS Source Type: research
Authors: Moffat GT, O'Reilly EM Abstract Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy that remains a challenge to treat. In pursuit of personalized medicine, researchers continue active exploration of the genetic and molecular framework of PDAC to apply novel therapeutics and enhance outcomes. In patients who have PDAC, germline mutations-such as those in the BRCA1/2 and PALB2 genes-are predominantly associated with the DNA damage response and repair pathway. On the basis of studies completed in patients with BRCA-mutated advanced breast and ovarian cancer, the poly(ADP-ribose) polymerase (PA...
Source: Clinical Advances in Hematology and Oncology - Category: Cancer & Oncology Tags: Clin Adv Hematol Oncol Source Type: research
Conclusions: Our results highlight the role of WNT/PCP signaling in ovarian cancerogenesis, indicate a possible therapeutic potential of CK1 inhibitors for HGSC, and strongly suggest that the detection of WNT pathway inducing activity ascites (or WNT5A levels in ascites as a surrogate marker) could be a novel prognostic tool for HGSC patients.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Conclusion: Our findings provided an effective strategy to compensate for the congenital defects of some small molecule inhibitors and thus enhanced the therapeutic efficacy of ovarian cancer.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
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