The effect of low and ultra-low oxygen tensions on mammalian embryo culture and development in experimental and clinical IVF.

This article reviews the literature data of the last four decades and discusses the current evidence on the use of low and ultra-low O2 in embryo culture, and examines the impact of multiple factors on IVF outcomes.Abbreviations: O2: oxygen tension; IVF: in vitro fertilization; IVC: in vitro culture; ET: embryo transfer; ROS: reactive oxygen species; ARTs: assisted reproductive technologies.
PMID: 32379506 [PubMed - as supplied by publisher]

Source: Systems Biology in Reproductive Medicine - May 6, 2020 Category: Reproduction Medicine Authors: Belli M, Antonouli S, Palmerini MG, Bianchi S, Bernardi S, Khalili MA, Donfrancesco O, Nottola SA, Macchiarelli G Tags: Syst Biol Reprod Med Source Type: research