Do Serum Urate –Associated Genetic Variants Differentially Contribute to Gout Risk According to Body Mass Index? Analysis of the UK Biobank

ConclusionThe association of a urate GRS with gout is mildly attenuated in obese individuals compared to overweight individuals. However, genetic variants have a strong effect on gout risk in those with overweight and obese BMIs, with an effect similar to that observed in low/normal BMI.

Source: Arthritis and Rheumatology - May 1, 2020 Category: Rheumatology Authors: Vicky Tai, Ravi K. Narang, Greg Gamble, Murray Cadzow, Lisa K. Stamp, Tony R. Merriman, Nicola Dalbeth Tags: Original Article Source Type: research