Tinnitus discovery opens door to possible new treatment avenues
For tens of millions of Americans, there's no such thing as the sound of silence. Instead, even in a quiet room, they hear a constant ringing, buzzing, hissing, humming or other noise in their ears that isn't real. Called tinnitus, it can be debilitating and life-altering.Now, University of Michigan Medical School researchers report new scientific findings that help explain what is going on inside their unquiet brains.The discovery reveals an important new target for treating the condition. Already, the U-M team has a patent pending and device in development based on the approach.
CONCLUSIONS In this retrospective review, sectioning of the NI produced no major complications, such as permanent facial weakness or deafness, and was effective for patients when performed in addition to other procedures. After sectioning of the NI, patients experienced 4.8 years pain free and experienced 6.2 years of less pain than before surgery. Alone, sectioning of the NI was not effective. The pathophysiology of NIN is not entirely understood. It appears that neurovascular compression plays only a minor role in the syndrome and there is a high degree of overlap with TN. PMID: 30117769 [PubMed - as supplied by publisher]
CONCLUSIONS: Although a number of studies aimed to evaluate whether or not one type of cerumenolytic is more effective than another, there is no high-quality evidence to allow a firm conclusion to be drawn and the answer remains uncertain.A single study suggests that applying ear drops for five days may result in a greater likelihood of complete wax clearance than no treatment at all. However, we cannot conclude whether one type of active treatment is more effective than another and there was no evidence of a difference in efficacy between oil-based and water-based active treatments.There is no evidence to show that using ...
Conclusion: Losartan might prevent axonal sprouting after hearing loss by blocking TGF-β signaling thereby preventing maladaptive auditory-somatosensory plasticity. PMID: 30021416 [PubMed - as supplied by publisher]
This study aims to explore the efficacy and long-term effects of acupuncture in patients with ISSNHL. This study will be a randomized controlled trial with strict methodology and few design deficits. If our study yields positive results, acupuncture could be recommended as a salvage therapy for patients with ISSNHL.Trial registrationChinese Clinical Trial Registry,ChiCTR-ICR-15006787. Registered on 12 July 2015.
New research suggests that mindfulness-based cognitive therapy relieves the severity of tinnitus considerably, compared with other relaxation techniques.
Abstract We performed a cluster analysis to classify the audiogram shape in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). We also investigated whether the audiogram shape is a prognostic indicator in the management of ISSNHL. A total of 115 inpatients with ISSNHL treated between 2001 and 2010 were analyzed. The data collected included age, sex, duration of hearing loss at the time of treatment, and the presence or absence of tinnitus, vertigo, diabetes, nystagmus, and canal paresis. A hierarchical cluster analysis was performed using the hearing threshold for each frequency on audiograms as ...
Condition: Tinnitus, Subjective Intervention: Device: Transcranial electrical stimulation (tES) Sponsors: Northwestern University; National Institute on Deafness and Other Communication Disorders (NIDCD) Not yet recruiting